Here's an observation about RPG that I was verifying with a little research yesterday. Although there have been many, many RPG with humor as a key part (Bard's tale) or incidental jokes (most), there aren't any "Great Classic RPGs" that have been drawn and expressed as cartoon art. They are all as realistic as the graphics of the time would allow. That doesn't mean there are no cartoon style RPGs. For instance, I think Dragon Quest has very serious games in terms of having combat, spells, party, items, crafting, big worlds, etc. all part of a well-thought out whole. The cartoons work well on the DS where most DQ games are native. There are also many, many others which are small and lesser known, especially on-line games.
Now obviously it's a stock artistic convention that heroes/heroines out saving the Universe are bigger/stronger/more beautiful/more scantily dressed (if female) than the NPCs, and obviously it's appealing to think of yourself as your bigger/stronger/etc. avatar. But does that mean a player couldn't relate to an avatar who is funny-looking? Or could it be part of the role play to say Yeah, I'm funny looking: but I can still go out and save the Universe?